Police seized nearly $82,000 in drugs and more than $40,000 in property following search warrants executed in Barrie, Owen Sound, Grey County and Bruce County.
OPP and police services from Barrie and Owen Sound carried out the raids on Thursday.
As a result of the search warrants, police say they seized cocaine, crack cocaine, meth, Fentanyl and oxycodone.
Officers also seized a variety of property including cell phones, digital scales, drug trafficking paraphernalia, Canadian and non-Canadian currency, two rifles and three vehicles.
A 60-year-old Barrie man was charged with 14 criminal offences related to drugs, weapons and failure to comply with a probation order.