A motorcycle and an SUV collided on the 20th Sideroad and the 2nd Line of Innisfil, resulting in serious injuries to the bike rider.
The crash happened shortly after 5 p.m. on Sunday.
South Simcoe Police said a 47-year-old Innisfil man was airlifted to a Toronto trauma centre where he is in stable condition.
A 17-year-old Cookstown girl, driving the SUV, was treated at the scene for a minor injury.
Police said the SUV was travelling eastbound on the 2nd Line when it collided with the northbound motorcycle.
The investigation is ongoing. Anyone with information regarding this collision is asked to contact South Simcoe Police or Crime Stoppers.